Science fiction blends with domestic horror in this thriller. Spencer Armacost (Johnny Depp) is an astronaut on a routine mission in space when something goes horribly wrong and it looks as if hes doomed. However, Spencer is rescued at the last moment and returns to earth a hero. He soon announces that hes retiring from space exploration to spend more time with his wife Jillian (Charlize Theron). Jillian has suffered from depression in the past and would like to start a family, so shes initially thrilled with Spencers decision. Jillian soon finds herself pregnant, but she starts to notice something odd about her husband, as if the man who returned isnt quite the same person who went away. As her pregnancy advances, Jillians anxieties increase, but has something really happened to Spencer, or have Jillians old demons merely resurfaced? The Astronauts Wife marked the directorial debut of Rand Ravich, who previously penned screenplays for such films as The Maker and Candyman: Farewell to the Flesh. ~ Mark Deming, All Movie Guide