Determined to free a lab full of animals from a grim fate in the confines of a scientific experimentation facility, a group of young animal rights activists unwittingly releases a malevolent evil in director Simon De Selvas horror-flavored hriller. When an alarm is tripped mid-mission and the animal liberators make a hasty retreat, they are alarmed to find that one of the activists was left behind in the chaos. In the days that follow, the remaining members of the group all receive a mysterious e-mail with the subject header Lethal Dose and a map of a vivisection lab. Gathering together to break into the abandoned lab and solve the mystery of the elliptical e-mails, the group members soon find themselves the subjects of a complex and deadly experiment. ~ Jason Buchanan, All Movie Guide